A postdoctoral position is available in the Herman B Wells Center for Pediatric Research at the Indiana University School of Medicine. Our lab is involved in the diagnosis and investigation of molecular mechanisms underlying rare genetic autoinflammatory diseases. To these ends, we are developing both in vivo and in vitro models using genetically modified mice, primary patient samples, pluripotent stem cells and engineered cancer cell lines.
Our team seeks to understand the genetic and biochemical regulation of innate immune signal transduction pathways implicated in a class of medical conditions that disrupt normal regulation of immune system function. Working knowledge of routine clinical immunology lab assays, and prior experience working with limited quantities of human samples and handling mice is desirable. Familiarity with R programming language, or an interest in acquiring basic R skills and other computational tools is required.
This position will involve learning and effectively utilizing a variety of biochemical and molecular techniques as well as the ability to handle and monitor small animals. Duties and responsibilities include performing in vivo characterization of mouse models and cell culture experiments.
This research makes extensive use of cell and molecular biology techniques and includes small animal (mouse) handling and dosing. Mouse handling techniques include peritoneal and tail vein injection of mice, performing cheek bleeds, dissection and cell harvest, primary and cancer cell culture, DNA transfection, qPCR, immunoblot, and immunofluorescence.
PhD in Biochemistry, Molecular or Cell Biology, Immunology, or a related field and/or MD with an interest in Immunology and Genetics. The candidate should be able to work closely with others in a team setting as well as independently. The candidate will be trained to design and conduct experiments, and must have effective oral and written communication skills. Prior experience or willingness to work with animal models is required.
Department Contact for Questions:
Eric Hanson email@example.com
OAA #: IUSM006862016
Internal Number: 8402
About Indiana University
Founded in 1820, Indiana University is the state’s public university system, comprised of two core campuses—IU-Bloomington and IUPUI—and six regional campuses located throughout the state. Combined, the total student population is more than 114,000 undergraduate, graduate and professional school students. IU is one of the largest employers in the state, with over 20,000 faculty and staff. Indiana University is an equal employment and affirmative action employer and a provider of ADA services. Diversity and inclusion remains a core commitment to IU’s mission to cultivate an educational environment that supports equal access, participation and representation on all of its campuses and that provides educational and career opportunities for all.